puriFlash^® MS
puriFlash^® MS-HWM
& MS Splitter

Mass-triggered fraction collection via normal or reverse-phase Flash or preparative Chromatography.
Confirmation of the mass and purity of the collected fractions
Real-time reaction monitoring
Compact spectrometer that can be positioned underneath a fume hood, direct analyses

Characteristics

Source ESI, APCI or APCI/ASAP (Optional)
A single analysis for positive and negative ion mode
Flow ESI: 10 µL/min to 1 mL/min
Flow APCI: 10 µL/min to 2 mL/min
Flow ASAP: 10 µL/min to 2 mL/min
puriFlash^® MS range: 10 to 1200 m/z
puriFlash^® MS-HMW range: 10 to 2000 m/z
Acquisition frequency per second 10,000 m/z
Sensitivity (ESI) 10 pg reserpin (FIA – injection of 5 µL to 100 µL/min) S/N: 100/1 (RMS) with SIM of m/z 609.3
Accuracy +/- 0.1 m/z for the entire acquisition range
Stability +/- 0.1 m/z for a period of 12h (18°C -24°C)
Polarity-change speed: 50 ms

Injection

Direct injection (FIA) or ASAP source
The injection valve on the front side allows direct introduction of the diluted compounds before purification
The target masses are automatically transferred into the purification method for the purpose of collection
Liquid or solid samples can be introduced directly into the source using the ASAP source

Required for the functioning of the system

Nitrogen 60 psi >98 % purity
Gas consumption <10 L/min
Solvent grade LC/MS

MS Splitter

Interchim^® Concept
Combined “Split and Dilution” Technology
Compatible with all column sizes
Even with a high flow, no counterpressure is generated
Dilution after split to adjust the quantity entering the source and to avoid system saturation

Software

Entirely controlled via the Intersoft X Software
Automatic and standardized scale for every signal (MS, UV, DEDL) up to 6 detection channels
Real-time mass spectrum
Mass spectrum at a given time