Mass spectrometers : puriFlash® MS
Mass spectrometers : puriFlash® MS
Your purification workflow simplified: Experience Mass Directed Purification your way on both Flash & PrepLC systems
Reduce your purification workload up to 50% with the specificity of mass detection, no more fraction guesswork
puriFlash® MS
puriFlash® MS-HMW
& MS Splitter
Our multifunctional and compact
mass spectrometers and
our MS Splitter for perfecting
your purification platform
Mass Directed Purification for Flash & Prep
Time is precious in the lab. With mass-directed purification, chemists get pure compounds faster and with fewer steps—saving hours each week. Advion Interchim Scientific® already offers the industry-leading PrepLC-MS integration, and now seamlessly integrates our Flash purification offerings as well. With the puriFlash® XS 530 coupled with the expression® Compact Mass Spectrometer (CMS) you can:
- Collect only your peaks of interest
- Reduce or eliminate the need for fraction analysis with confidence,
knowing you collected your peak of interest - Reduce the burden of drying down unnecessary fractions
Detect and collect your compounds by molecular weight thanks to the seamless expression® CMS & puriFlash® workflow
Ultra easy :
By normal or reverse-phase Flash or preparative Chromatography, you start collecting your fractions by mass.
Ultra quick :
Before purification, the diluted sample can be injected through the direct injection valve in order to visualize the mass existing in the product and to record it in the purification method for the purpose of collection.
Ultra accurate :
You can rely on puriFlash® MS 100%. But if you would like to make sure that everything went right, you just have to ask: puriFlash® MS will confirm the mass and purity of the collected fractions.
Require Individual Fraction Analysis
No More Fraction Guesswork!
Collect your compound of interest faster than ever with no tedious and time-consuming fraction analysis, just mass-directed purification.
And if it is from an ASAP source, proceed with step 2
& add them to your
purification method
Looking for your perfect Flash-MS solution?
Download our application note to learn more.
In this application note, we compare the use of a flash chromatography system with a UV detector alone versus the same system paired with a mass spectrometer. The data highlights the impact on workflow efficiency and the importance of selecting the appropriate splitter.
Real-time monitoring of chemical reactions.
Whether you are using our mass spectrometers alone or in combination with a puriFlash®, all you have to do is inject your product directly into the mass to be able to follow the reactions in real time. It is as simple as that.
Direct analyses always at hand
Forget about endless waiting in front of the MS platforms. Our spectrometers are compact and can be positioned underneath a fume hood to optimize your work flow and the productivity of your laboratory.
Product-specific mass spectrometers
Independent of their molecular weight.
Our range of mass spectrometers has been designed taking into account the daily challenges of chemists who are developing the organic synthesis and the purification.
Our only design requirement: puriFlash® MS must fully meet your needs, no matter whether you are working with small or large molecules
puriFlash® MS
Dedicated to small molecules, puriFlash® MS becomes an ally of the chemists because essential information is available within record time.
Due to its multi-functionality, puriFlash® MS is the ideal partner you will no longer want to do without.
puriFlash® MS
10 to 1200 M/Z
puriFlash® MS-HMW
(High Molecular Weight)
This system combines all advantages of puriFlash® MS therefore it is perfect for applications with large molecules such as peptides or biomolecules.
With the ESI source and the possibility of multiple charging, compounds with a molecular weight of more than 1200 m/z can be detected.
puriFlash® MS-HMW
10 to 2000 M/Z
APCI, ESI or ASAP, you choose the preferred ionization source for your compounds.
puriFlash® MS systems can be equipped with two types of atmospheric pressure sources for soft ionization :
– APCI (for Atmospheric Pressure Chemical Ionization)
– ESI (for Electrospray Ionization).
The ASAP source is available as an option. It allows direct injection of liquid samples without prior dilution as well as the injection of solid samples for immediate compound identification.
More information on sources
Get the best out of our unique interface :
Split and Dilution.
And work without flow or concentration limitations
Our innovative interface « Split and Dilution Technology » makes it possible to combine the puriFlash® system and the puriFlash® MS thanks to the MS Splitter. Since this interface does not generate any counterpressure, even if the flow is high, you can work with all kinds of column dimensions and all of the puriFlash® 5 systems.
The postdilution integrated into this interface allows the injection of samples without concentration limitations and without the risk of detector saturation.
Get the best out of our unique interface :
Split and Dilution.
And work without flow or concentration limitations
Our innovative interface « Split and Dilution Technology » makes it possible to combine the puriFlash® system and the puriFlash® MS thanks to the MS Splitter. Since this interface does not generate any counterpressure, even if the flow is high, you can work with all kinds of column dimensions and all of the puriFlash® 5 systems.
The postdilution integrated into this interface allows the injection of samples without concentration limitations and without the risk of detector saturation.
